The Grayson family is a pillar of the African-American community in New Orleans. But Sylvia Grayson, the matriarch, has deep secrets that she represses under a veneer of keeping up appearances. She keeps a tight rein on her daughter, Olivia, and has the perfect life mapped out for her: go to college, join the Delta sorority, marry the proper boy. So when the town's "bad girl" is found murdered one summer day in 1975, Sylvia pulls Olivia even closer. But when Olivia's one last attempt at rebellion is subverted by her mother, Sylvia's relentlessly tight control shatters the ties between them.
Years later, Olivia's own daughter, Rachelle, is trying to make her way in the world. Olivia does not want to make the same mistakes as her mother, nor does she want her daughter to make the same errors Olivia made out of rebellion. Meanwhile, a killer is watching from the shadows, determined to keep the secrets of the past from coming to light. The Delta Sisters is a spellbinding, intimate portrait of what happens when these passionate women have to join together at last in the face of danger.