This volume contains 88 research articles written by prominent researchers. The articles are chosen from a large international conference on high performance computing and its applications held in Shanghai, China. Topics covered include a variety of subjects in modern high performance computing and its applications, such as the design and analysis of high performance computing algorithms, tools and platforms, and their scientific, engineering, medical, and industrial applications. The book serves as an excellent reference work for graduate students and researchers working with high performance computing for problems in science and engineering.