The two volumes "Science of Synthesis: Multicomponent Reactions" critically review the state of the art of domino, sequential, and consecutive multicomponent reactions in what is a highly dynamic field. They serve as the basis for practical application to reach the goals of diversity-oriented synthesis, reaction design, and novel synthetic concepts. As is typical for the Science of Synthesis series, the reference work on multicomponent reactions presents the best synthetic methods as judged by experts in the field and includes typical and general experimental procedures.


The volume "Reactions Involving a Carbonyl Compound as Electrophilic Component" covers the following topics:






Biginelli Reaction
Strecker Reaction
Hantzsch Pyridine Synthesis
Mannich Reaction
Petasis Reaction
Willgerodt-Kindler Reaction
Kabachnik-Fields Reaction
Passerini Reaction
Ugi Reaction
Gewald Reaction

Contributions by: Maria Jose Arevalo Caballero, Muhammed Ayaz, Luca Banfi, Andrea Basso, Luca Bernardi