In this thorough revision and update of their classic text, the authors describe the impact of recent economic and structural changes in health care on the role of the medical family therapist. They describe how medical and mental health providers can learn to speak the same language, whether they collaborate in outpatient therapy, co-location settings, community health centers, or fully-integrated health systems. They also take into account exciting new advances in fertility treatments and genomic medicine, and assess the medical family therapist's role in navigating the unique conflicts that can arise in families dealing with these and similar issues.