In this book, we introduce fundamental concept concerning comprehensive statistical and algorithmic techniques in the foremost streamline of computer science and engineering. We present the concept of computational intelligence methods and specific analysis along with examples and case studies from the perspective of a broad coverage and clear exposition of the subject matter. This text is designed for a swift overview and the tools required for solving problems for both the researchers and students. Herewith, this study offers all basic existing dimensions of computer science and engineering theories and computational intelligence algorithms, centrally working towards contemporary modern real-world applications including biological data interpretations and gene feature selections, image enhancement algorithms, IPv6 generator, as well as the fuzzy clustering approach and perspective computing schemes.