While preserving the clear, accessible style of previous editions, this fourth edition reflects the latest developments in computer-intensive methods that deal with intractable analytical problems and unwieldy data sets. This edition summarizes relevant general statistical concepts and introduces basic ideas of nonparametric or distribution-free methods. Designed experiments, including those with factorial treatment structures, are now the focus of an entire chapter. The book also expands coverage on the analysis of survival data and the bootstrap method. The new final chapter focuses on important modern developments. With numerous exercises, the text offers the student edition of StatXact at a discounted price.