This volume contains a collection of papers suggested by the Scientific Committee that includes the best papers presented in the 2nd International Conference (CHAOS2009) on Chaotic Modeling, Simulation and Applications, that was held in Chania, Crete, Greece, June 1-5, 2009. The aim of the conference was to invite and bring together people working in interesting topics of chaotic modeling, nonlinear and dynamical systems and chaotic simulation.The volume presents theoretical and applied contributions on chaotic systems. Papers from several nonlinear analysis and chaotic fields are included and new and very important results are presented. Emphasis was given to the selection of works that have significant impact in the chaotic field and open new horizons to further develop related topics and subjects. Even more the selected papers are addressed to an interdisciplinary audience aiming at the broad dissemination of the theory and practice of chaotic modeling and simulation and nonlinear science.