This book presents the best papers from the International Conference on Data Science for Computational Security (IDSCS 2025), organized by CHRIST (Deemed to be University), Bangalore, India, from 14–15 November, 2025. This book targets the current research works in the areas of data science, data security, data analytics, artificial intelligence, machine learning, computer vision, algorithm design, computer networking, data mining, big data, text mining, knowledge representation, soft computing, and cloud computing.