Metabolic engineering is the actual engineering of metabolism-the reactions that sustain life. This book covers the need for cell engineering by starting off with several applications of plants and microbes followed by the approaches. The application of artificial intelligence(AI) and machine learning(ML) in this field, along with case studies, has also been covered. This becomes pertinent given the entry of this field in almost all aspects of living! Several examples of metabolic engineering have been covered to enable a reader to be aware of the concepts and developments.