Diabetes mellitus (DM) , is a group of metabolic diseases in which there are high blood sugar levels over a prolonged period, associated with various complication. Globally, as of 2013, an estimated 382 million people have diabetes worldwide, with type 2 diabetes making up about 90% of the cases. An estimated one out of every four people with diabetes has the disease and does not know it. Knowing their risk for type 2 diabetes helps patients take steps toward prevention. Book places emphasis on Patho-physiology of diabetes and its complications and use of research methodology for accurate results .it comprises clearly understandable, illustrative diagrams and tables for easy adaptability and reproducibility This book contains an amalgamation of the essentials of basic and advanced knowledge of Diabetic and its Complication.