This book constitutes the refereed proceedings of the 6th International Conference on Parallel Problem Solving from Nature, PPSN VI, held in Paris, France in September 2000. The 87 revised full papers presented together with two invited papers were carefully reviewed and selected from 168 submissions. The presentations are organized in topical sections on analysis and theory of evolutionary algorithms, genetic programming, scheduling, representations and operators, co-evolution, constraint handling techniques, noisy and non-stationary environments, combinatorial optimization, applications, machine learning and classifier systems, new algorithms and metaphors, and multiobjective optimization.