This text on biochemical engineering covers such topics as artificial neural networks in bioprocess state estimation; the use of regulated secretion of protein production from animal cells; and immuno-chemically based assays for process control.

Contributions by: D.J. Barnes, I. Economidis, I. Endo, A. Fiechter, S. Furusaki, G.E. Grampp, H. Hakanson, M.N. Karim, I. Karube, B. Mattiasson, J. Nielsen, S.L. Rivera, A. Sambanis, M. Seki, S. Shioya, B. Sonnleitner, G.N. Stephanopoulos, T. Takeuchi