This volume illuminates patterns among eight prominent US innovations in science and mathematics education: California's reform of science education, ChemCom, Contemporary Precalculus, Kids Network, Project 2061, NCTM Standards, Urban Mathematics Collaboratives, and Voyage of the Mimi. Reformers devised new strategies to effect large-scale change. The advocated conceptions of science and mathematics emphasize integration across subjects and applications of concepts. Teachers played strong roles in the development of innovations and engaged their students to learn in new ways. The burdens of change created struggles between making changes significant and attenuating them to traditional practice. Innovators often underplayed assessment of student achievement, evaluation of the reforms, and issues of equity and inclusion.