The book is aimed at providing an understanding of basic principles and practices of Biostatistics. Attempt has been made to give a comprehensive inside into the basic concepts of biostatistics i.e. sound easy to read, relevant and useful to students and practitioners of biostatistics. The book includes the design of clinical trials and epidemiological studies collection of data, research methods, clinical measurement and sample size, calculations for various study designs. This makes it a handbook of biostatistics for students and researchers for agriculture, veterinary, life sciences, medicine, public health, biological and social sciences.