Former journalist Hannah Harker is on the run after committing an atrocity which has stunned the world. A beautiful but fragile Brazilian aid worker uncovers a hideous experiment being carried out by a sinister pharmaceutical company. A young gangster struggling for survival on the streets of Tokyo is preparing to risk everything to find a cure for his mother's psychosis. The paths of these three strangers will converge in an extraordinary orgy of violence, vodka and sex and together they will come face to face with the dark heart of pure evil.