During the Depression, silicosis, an industrial lung disease, emerged as a national social crisis. Experts estimated that hundreds of thousands of workers were at risk of disease, disability, and death by inhaling silica in mines, foundries, and quarries. By the 1950s, however, silicosis was nearly forgotten by the media and health professionals. Asking what makes a health threat a public issue, David Rosner and Gerald Markowitz examine how a culture defines disease and how disease itself is understood at different moments in history. They also explore the interlocking relationships of public health, labor, business, and government to discuss who should assume responsibility for occupational disease.