The Shrikhande graph, discovered by Indian Mathematician Sharadchandra Shankar Shrikhande in 1959, exhibits several unusual properties and occupies a pivotal position within discrete mathematics. Offering a unique introduction to graph theory and discrete mathematics, this book uses the example of the Shrikhande graph as a window through which these topics can be explored. Providing historical background, including the Euler conjecture and its demise, the authors explore key concepts including: Cayley graphs; topological graph theory; spectral theory; Latin squares; root systems. A novel and valuable resource for graduate students and researchers interested in graph theory, its history, and applications, this book offers a comprehensive exploration of the Shrikhande graph and its significance.