This contributed volume celebrates the work of Tayfun E. Tezduyar on the occasion of his 70th birthday. The chapters it contains were born out of the Advances in Computational Fluid-Structure Interaction and Flow Simulation (AFSI) conference, also dedicated to Prof. Tezduyar and held in Sapporo, Japan in August 2024. The contributing authors represent a group of international experts in the field who discuss recent trends and new directions in computational fluid dynamics (CFD) and fluid-structure interaction (FSI). Chapters explore topics such as mathematical methods and data-driven and reduced-order models; novel methods and applications in CFD; computational FSI and multi-physics models; wind energy applications; and automotive applications. Researchers, practitioners, and advanced graduate students working on CFD, FSI, and related topics will find this collection to be a definitive and valuable resource.