This book summarizes the main results achieved in a four-year European Project on nonlinear and adaptive control. The project involves leading researchers from top-notch institutions: Imperial College London (Prof A Astolfi), Lund University (Prof A Rantzer), Supelec Paris (Prof R Ortega), University of Technology of Compiegne (Prof R Lozano), Grenoble Polytechnic (Prof C Canudas de Wit), University of Twente (Prof A van der Schaft), Politecnico of Milan (Prof S Bittanti), and Polytechnic University of Valencia (Prof P Albertos).The book also provides an introduction to theoretical advances in nonlinear and adaptive control and an overview of novel applications of advanced control theory, particularly topics on the control of partially known systems, under-actuated systems, and bioreactors.