Clinician's Manual on Cystic Fibrosis is a concise review, which discusses pathophysiology, clinical features, diagnosis, symptom control, and standard and emerging disease-modifying therapies. The text will be adapted for the global audience based on the Clinical Guidelines: Care of Children with Cystic Fibrosis by the Royal Brompton Hospital. Busy healthcare professionals who want a quick review of diagnostic and staging guidelines as well as a summary of current therapies for cystic fibrosis will benefit from this succinct guide.