This book presents selected papers from International Conference on Multi-Strategy Learning Environment (ICMSLE 2025), held at Graphic Era Hill University, Dehradun, India, during 26–27 February 2025. This book presents current research in machine learning techniques, deep learning theories and practices, interpretability and explainability of AI algorithms, game theory and learning, multi-strategy learning (MSL) in distributed and streaming environments, and adaptive data analysis and selective inference.